Now eligible for reimbursement from Medicare and Medicare Advantage! Learn More
$2,107.97
Hospital Outpatient (APC 5054)
$1,064.49
Physician (Non-Facility)
20 weeks
CMS Coverage

*Facility (MPFS): $83.84

G0460 - Non-diabetic chronic wounds

Contractor Priced

no national rate established

National Coverage

Our proprietary, patented technology delivers the healing power of advanced biologic products with national coverage from Medicare and Medicare Advantage Plans.

What’s Covered

ActiGraftPRO® system is described by the National Coverage Determination (NCD 270.3) as a blood-derived product and is eligible for reimbursement with HCPCS G0465.

Centers for Medicare & Medicaid Services (CMS) will reimburse autologous PRP for the treatment of chronic non-healing diabetic wounds for a duration of 20 weeks, when prepared by devices whose Food and Drug Administration (FDA)-cleared indications include the management of exuding cutaneous wounds, such as diabetic ulcers.

  • The PRP is different from previous products in that it contains whole cells including white cells, red cells, plasma, platelets, fibrin, stem cells, and fibrocyte precursors.
  • The PRP is used by physicians in clinical settings in treating chronic, non-healing wounds, cutaneous wounds, soft tissue and bone.

Coverage of autologous PRP for the treatment of all other chronic non-healing wounds will be determined by local MACs.

HCPCS Codes

  • HCPCS G0465 – diabetic chronic wounds, FDA-cleared device

Autologous platelet-rich plasma (PRP) or other blood-derived product for diabetic chronic wounds/ulcers, using an FDA-cleared device for this indication, (includes as applicable administration, dressings, phlebotomy, centrifugation or mixing, and all other preparatory procedures, per treatment).

  • HCPCS G0460 – non-diabetic chronic wounds

Autologous platelet-rich plasma or other blood-derived product for non-diabetic chronic wounds/ulcers, including as applicable phlebotomy, centrifugation or mixing, and all other preparatory procedures, administration, and dressings, per treatment

Diagnoses Codes

ActiGraftPro system requires two diagnosis codes 

For claims with dates of service on or after July 1, 2023, PRP, for the treatment of chronic non-healing diabetic wounds must be billed reporting both an ICD-10 diagnosis code for diabetes mellitus and an ICD-10 diagnosis code for chronic ulcers.

  • Diabetic Mellitus ICD-10-E
  • Chronic Ulcers ICD-10-L

*Disclaimer: The information provided shall not be constructed as a statement, promise, or guarantee that reimbursement will be received. Reimbursement requirements are subject to change at any time. Check with your local payer regularly.

NCD 270.3 coverage applies to the following site of service:

  • POS 11 – Office
  • POS 19 – Off-campus hospital outpatient
  • POS 22 – On-campus hospital outpatient
  • POS 49 – Independent clinic
  • POS 12 – Home/private residence
  • POS 31 – Skilled Nursing

Disclaimer: MPFS payment applicable to Part B Patient

Hospital Outpatient Wound Centers-19 & 22

Independent Wound Care Clinics -49

Private Practice- 11

Home -12

Skilled Nursing-31

The ActiGraft Coverage Support Program with Legacy Medical Consultants

RedDress is committed to supporting physicians and facilities using the ActiGraft® system to benefit their patients. Through its partnership with Legacy Medical Consultants, the ActiGraft Coverage Support Program delivers dedicated reimbursement and access support to help expand use of the ActiGraft Procedure. Legacy Medical Consultants assists with prior authorization, coding, billing, and reimbursement questions to enable seamless adoption.

We are just a phone call away to help you and your patients navigate the insurance coverage process.

+1 (817) 961-1288
Monday – Friday, 8:30am – 5:00pm EST

Ready to reimagine your approach to wound healing?

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