More Comfortable, More Affordable Healing

Chronic wounds can be painful, uncomfortable, and difficult to treat. ActiGraft® system is an innovative wound management solution that supports the natural wound healing processes of the body. 

What is ActiGraft?

ActiGraft is a first-of-its-kind chronic wound treatment that uses a patient’s own blood to create an in vitro blood clot. This blood clot is then applied to the wound, where it supports the natural wound healing processes of the body.

How does ActiGraft work?

When injured, your skin is capable of repairing itself and healing the wound. This happens through 4 overlapping processes—hemostasis, inflammation, proliferation and remodeling. For these processes to work, it’s essential that blood can get to the site of the wound. However, factors like illness, poor circulation, continued pressure, etc. can prevent blood flow to the wound and hinder the healing process. When this happens, an ulcer may form.

ActiGraft enables health care providers to produce—in real time—in vitro blood clots from the patient’s blood. Applying this blood clot to the site of the wound recreates the natural wound healing environment, and supports the body’s own healing processes.

What are the benefits of ActiGraft?

ActiGraft revolutionizes the way we treat chronic wounds and delivers significant benefits in terms of comfort and cost.


  • Applied weekly (as opposed to daily for other treatments), meaning less wound interaction.
  • Created from the patient's blood, better assuring compatibility.


  • Provides the wound with an optimal healing environment, allowing the healing process to proceed unhindered.
  • Delivers fast healing.


  • Blood clot created from the patient’s own blood, not requiring an external source (such as animal or synthesized) for raw material, keeping costs down.
  • Designed with nurses in mind, ActiGraft can be prepared at the patient's bedside in 12 minutes and requires no capital equipment.
  • May be covered by Medicare and other forms of insurance.

What are people saying about ActiGraft?

“I recommend this to anybody that had a sore like I had for so long.”

- Ellen S., Patient, West Revere Health Center

“My general rule is if I don’t see improvement in a couple of weeks, I change the treatment and that can be a vicious cycle…with this you didn’t have to change the treatment, it healed.”

- Gail W., Director of Nurses, Phillips Manor

“After a week, after the first dressing the wound bed looked beefy red, no drainage, no smell.”

- Esther O., Unit Manager, West Revere Health Center

“ActiGraft is a highly efficacious product that patients love, it has changed how we treat patients across the care continuum.”

- Dr. Bryan Doner, DO, D&P Medical Group

“It is very easy, its only once a week, it shows great results. The wound bed stays healthy, looking moist.”

- Nina Brophy, RN, Bear Hill Rehabilitation

"I was impressed with the consistent improvement in wound healing week to week with ActiGraft. I will be looking for more patients to switch to ActiGraft in my practice because beyond the results, the support I got from the company went above and beyond."

- Dr. Claire S., M.D., Melrose Surgical Associates

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Is ActiGraft the right treatment for my chronic wounds?

ActiGraft can be used for a wide variety of hard-to-treat chronic cutaneous wounds, including but not limited to:

  • Diabetic foot ulcers
  • Pressure injuries
  • Venous ulcers
  • Skin tears
  • Mechanically or surgically-debrided wounds

The Road to
Healing with ActiGraft

Hear the inspiring stories of real patients.

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Learn More about ActiGraft

Learn more about ActiGraft, how it works, and how you could benefit from a chronic wound treatment that supports the natural healing processes of your body.

See How Actigraft Works →

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